Working together to advance RNA vaccine development

The PATH RNA Cooperative is a trusted, noncompetitive, manufacturer-driven group that accelerates RNA vaccine development from early research to first-in-human trials. It equips selected low- and middle-income country vaccine manufacturers with hands-on expertise, shared knowledge, and collaborative resources; drives collective learning; and facilitates access to standardized approaches and strategic insights that can strengthen manufacturing and advance access to lifesaving vaccines. 

About the RNA Cooperative

The RNA Cooperative is a small group of emerging market vaccine manufacturers and global nonprofit organizations working together to advance RNA vaccine development and manufacturing. The Cooperative fosters innovation and capacity building and supports multiple vaccine targets to build a foundation for broader regional impact and sustainable vaccine production. 

 

RNA vaccine technology is a flexible vaccine development approach able to rapidly generate safe and efficacious vaccines at large scale, but the technology has largely been inaccessible to low- and middle-income country vaccine manufacturers. During the COVID-19 pandemic, lower income countries were last in line to receive new vaccines and had vaccination rates that trailed far behind those of higher-income countries once they did—illustrating the importance of establishing RNA vaccine manufacturing to ensure equitable vaccine access at the local, regional, and global levels.

Convened and managed by PATH and funded by the Gates Foundation, the RNA Cooperative is made up of core and supporting members that work together to advance vaccine development:

  • Core members include low- and middle-income country vaccine manufacturers working to develop RNA vaccine manufacturing capabilities and capacity and to advance new RNA vaccine candidates
  • Supporting members include vaccine manufacturers, researchers, and nonprofit organizations providing resources and expertise related to RNA vaccine development.

The RNA Cooperative embodies the spirit and principles of a cooperative by promoting shared knowledge and collective learning to reach a common goal: greater access to advanced vaccine manufacturing technologies and, ultimately, a sustainable supply of lifesaving vaccines.   

Key Focus Areas

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    Preclinical

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    Process Development

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    Good Manufacturing Practice (GMP)

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    Clinical and Regulatory

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    Raw Materials

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    Lead Optimization

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    Artificial Intelligence (AI)